BDBM50033685 CHEMBL8290::Sodium; (2R,5R)-3-[2-hydroxy-eth-(Z)-ylidene]-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]heptane-2-carboxylate

SMILES OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C([O-])=O

InChI Key InChIKey=HZZVJAQRINQKSD-PBFISZAISA-M

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033685   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50033685(CHEMBL8290 | Sodium; (2R,5R)-3-[2-hydroxy-eth-(Z)-...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50033685(CHEMBL8290 | Sodium; (2R,5R)-3-[2-hydroxy-eth-(Z)-...)
Affinity DataIC50: >1.00E+6nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed